Lab Alumni
Roger Vogelmann
Former Postdoctoral Researcher
Current Position: Associate Medical Director at Universitätsmedizin Mannheim, Heidelberg University
Roger worked on how H. pylori affects epithelial cell polarity and the apical-junctional complex.
Fabio Bagnoli
Former Postdoctoral Researcher
Current Position: Project Leader at GSK Vaccines (Siena, Italy)
Fabio investigated how the H. pylori virulence factor CagA perturbs epithelial cell differentiation and polarity.
Mickey Pentecost
Former Graduate Student
Current Position: Chief Executive Officer at Diadem Biotherapeutics
Mickey studied how the bacterium Listeria monocytogenes invades the intestinal epithelium. He discovered that Listeria utilize breaches in cell polarity to access its receptor E-cadherin for invasion.
Elizabeth Joyce
Former Research Scientist
Current Position: Associate Adjunct Professor at UCSF
Elizabeth explored whether Yersinia enterocolitica has a similar mode of invasion of the intestinal epithelium as what we have previously shown for Listeria monocytogenes.
Lee Shaughnessy
Former Postdoctoral Researcher
Current Position: Scientist at Stratatech Corporation (Madison, WI)
Lee investigated how the intestinal pathogen Yersinia enterocolitica is able to access its host receptor B1 integrin when it is normally not exposed to the apical surface in polarized epithelia.
Shumin Tan
Former Graduate Student
Current Position: Assistant Professor of Molecular Biology & Microbiology at Tufts University School of Medicine
Shumin elucidated how H. pylori utilizes the cell surface as a replicative niche, and how H. pylori's virulence factors CagA and VacA directly benefit the bacterium by usurping host cell polarity and iron trafficking to enable colonization.
Michael Howitt
Former Graduate Student
Current Position: Assistant Professor of Pathology at Stanford University School of Medicine
Mike worked on chemotaxis regulatory mechanisms uniquely present in H. pylori and other Epsilonproteobacteria, and the role of chemotaxis in H. pylori colonization of the gastric glands.
Josephine Lee
Former Graduate Student
Current Position: Senior Scientist at 10X Genomics
Josephine developed a mouse model of H. pylori infection to look at the effects of the bacterial virulence factor CagA in vivo. Using this model, she also characterized host and bacterial factors that determine H. pylori localization in the stomach.
Renee Kwok
Former Research Assistant
Current Position: Clinical Laboratory Scientist at UCSF Mission Bay - Chemistry
Renee assisted Josephine Lee in characterizing a mouse model of H. pylori infection.
Diane Houben
Former Postdoctoral Researcher
Current Position: Project Manager/Scientist at Abera Bioscience
Diane used electron microscopy to visualize the interface of H. pylori's Type IV secretion system with the host cell surface.
Ryan Honaker
Former Postdoctoral Researcher
Current Position: Director of Microbiology at NomNomNow
Ryan studied H. pylori's response to epithelial cell adherence, and was developing a primary murine organoid gastric cancer model to study H. pylori infection.
Michael Sigal
Former Postdoctoral Researcher
Current Position: Fellow at Charite University Berlin, and Investigator at the Max Planck Institute for Infection Biology
Michael used a mouse model of H. pylori infection to discover that bacteria can colonize and activate gastric epithelial stem cells.
Julie Huang
Former Graduate Student
Current Position: Scientist at Caribou Biosciences
Julie studied the mechanisms that H. pylori uses to sense key signals in the stomach to find a specialized niche in the gastric epithelium where it can survive.
Lauren Popov
Former Graduate Student
Current Position: Scientist at Novome Biotechnologies
Lauren investigated how components of the host cellular adherens junctions control susceptibility to the Staphylococcus aureus virulence factor, α-toxin.
Connie Fung
Former Graduate Student
Current Position: Postdoctoral Researcher at Stanford University School of Medicine
Connie developed novel tools to visualize how gland-associated H. pylori populations establish, spread, and persist within the gastric mucosa, and found that the gland niche is important for chronic colonization.
Julia Co
Former Postdoctoral Researcher
Current Position: Scientist at Geltor
Julia developed reversed polarity human enteroids as a new model to study epithelial infections by microbes including Salmonella enterica and Listeria monocytogenes.
Roger Vogelmann
Former Postdoctoral Researcher
Current Position: Associate Medical Director at Universitätsmedizin Mannheim, Heidelberg UniversityRoger worked on how H. pylori affects epithelial cell polarity and the apical-junctional complex.
Fabio Bagnoli
Former Postdoctoral Researcher
Current Position: Project Leader at GSK Vaccines (Siena, Italy)Fabio investigated how the H. pylori virulence factor CagA perturbs epithelial cell differentiation and polarity.
Mickey Pentecost
Former Graduate Student
Current Position: Chief Executive Officer at Diadem BiotherapeuticsMickey studied how the bacterium Listeria monocytogenes invades the intestinal epithelium. He discovered that Listeria utilize breaches in cell polarity to access its receptor E-cadherin for invasion.
Elizabeth Joyce
Former Research Scientist
Current Position: Associate Adjunct Professor at UCSFElizabeth explored whether Yersinia enterocolitica has a similar mode of invasion of the intestinal epithelium as what we have previously shown for Listeria monocytogenes.
Lee Shaughnessy
Former Postdoctoral Researcher
Current Position: Scientist at Stratatech Corporation (Madison, WI)Lee investigated how the intestinal pathogen Yersinia enterocolitica is able to access its host receptor B1 integrin when it is normally not exposed to the apical surface in polarized epithelia.
Shumin Tan
Former Graduate Student
Current Position: Assistant Professor of Molecular Biology & Microbiology at Tufts University School of MedicineShumin elucidated how H. pylori utilizes the cell surface as a replicative niche, and how H. pylori's virulence factors CagA and VacA directly benefit the bacterium by usurping host cell polarity and iron trafficking to enable colonization.
Michael Howitt
Former Graduate Student
Current Position: Assistant Professor of Pathology at Stanford University School of MedicineMike worked on chemotaxis regulatory mechanisms uniquely present in H. pylori and other Epsilonproteobacteria, and the role of chemotaxis in H. pylori colonization of the gastric glands.
Josephine Lee
Former Graduate Student
Current Position: Senior Scientist at 10X GenomicsJosephine developed a mouse model of H. pylori infection to look at the effects of the bacterial virulence factor CagA in vivo. Using this model, she also characterized host and bacterial factors that determine H. pylori localization in the stomach.
Renee Kwok
Former Research Assistant
Current Position: Clinical Laboratory Scientist at UCSF Mission Bay - ChemistryRenee assisted Josephine Lee in characterizing a mouse model of H. pylori infection.
Diane Houben
Former Postdoctoral Researcher
Current Position: Project Manager/Scientist at Abera BioscienceDiane used electron microscopy to visualize the interface of H. pylori's Type IV secretion system with the host cell surface.
Ryan Honaker
Former Postdoctoral Researcher
Current Position: Director of Microbiology at NomNomNowRyan studied H. pylori's response to epithelial cell adherence, and was developing a primary murine organoid gastric cancer model to study H. pylori infection.
Michael Sigal
Former Postdoctoral Researcher
Current Position: Fellow at Charite University Berlin, and Investigator at the Max Planck Institute for Infection BiologyMichael used a mouse model of H. pylori infection to discover that bacteria can colonize and activate gastric epithelial stem cells.
Julie Huang
Former Graduate Student
Current Position: Scientist at Caribou BiosciencesJulie studied the mechanisms that H. pylori uses to sense key signals in the stomach to find a specialized niche in the gastric epithelium where it can survive.
Lauren Popov
Former Graduate Student
Current Position: Scientist at Novome BiotechnologiesLauren investigated how components of the host cellular adherens junctions control susceptibility to the Staphylococcus aureus virulence factor, α-toxin.
Connie Fung
Former Graduate Student
Current Position: Postdoctoral Researcher at Stanford University School of MedicineConnie developed novel tools to visualize how gland-associated H. pylori populations establish, spread, and persist within the gastric mucosa, and found that the gland niche is important for chronic colonization.
Julia Co
Former Postdoctoral Researcher
Current Position: Scientist at GeltorJulia developed reversed polarity human enteroids as a new model to study epithelial infections by microbes including Salmonella enterica and Listeria monocytogenes.